Recent trends and emerging strategies for aptasensing technologies for illicit drugs detection

Aptamers are ligand-binding oligonucleotide sequences with high affinities and selectivities towards their targets. Concomitantly, excellent recognition property has led to being adapted in analytical applications, drug, diagnostics, many other platforms the area of forensic science, respects, they superior analogous antibody-based assays. Recently, major progress been made biosensing applications aptamers that offer possibility rapid on-spot detection seized drugs or illegal substances. Furthermore, may facilitate a future advancement targeted delivery anti-narcotics progression therapy. Hence, this review article provides an overview electrochemical, optical, colorimetric aptasensors developed so far potential role narcotics detection. We advances aptamer sensing technology for cocaine, methamphetamine, codeine, opioid screening, obstacle at every stage aptasensor development is also discussed. Finally, innovative concepts using advanced nanomaterials different proposed new generation recreational